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Reason: This dataset can be shared by email request only as it will need approval by the depositor on an individual basis. For access to the data files, please contact research.data@kcl.ac.uk.

The English and Romanian Adoptees Brain Imaging Study – Alterations in adult brain structure associated with early childhood deprivation

dataset
posted on 2021-09-12, 20:08 authored by Nuria Mackes, Dennis Golm, Sagari Sarkar, Robert Kumsta, Graeme Fairchild, Mitul Mehta, Edmund Sonuga-Barke, The ERA Young Adult Follow-up team
The English and Romanian Adoptees Brain Imaging Study investigates the effects of early institutional deprivation on brain structure in young adulthood. This study analysed MRI data of young adults, who were exposed to severe deprivation in early childhood in the Romanian orphanages of the Ceaușescu era before being adopted by UK families. This dataset contains brain structural summary data of 67 Romanian adoptees and 21 non-deprived UK adoptees. Additionally, this dataset contains information on neurodevelopmental symptom domains, deprivation duration, birth weight, weight at entry into the UK and polygenic scores for total brain volume.

The English and Romanian Adoptees Brain Imaging Study has been funded by the Medical Research Council (MR/K022474/1). The Economic and Social Research Council funded the previous young adult follow-up (RES-062-23-3300). The study team acknowledges the support of the National Institute for Health Research Clinical Research Network (NIHR CRN).

Funding

LONG TERM NEUROBIOLOGICAL IMPACT OF EARLY DEPRIVATION: IMAGING YOUNG ADULT BRAIN STRUCTURE AND FUNCTION IN THE ENGLISH AND ROMANIAN ADOPTEES STUDY.

Medical Research Council

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The Economic and Social Research Council funded the previous young adult follow-up (RES-062-23-3300)

The study team acknowledges the support of the National Institute for Health Research Clinical Research Network (NIHR CRN).

History

Data collection from date

2014-07-17

Data collection to date

2019-02-05

Collection method

Structural MRI imaging, neuropsychological testing, questionnaires, interviews, DNA analysis.

Language

English

Copyright owner

Mackes, Nuria; Golm, Dennis; Sarkar, Sagari; Kumsta, Robert; Fairchild, Graeme; Mehta, Mitul; Sonuga-Barke, Edmund; The ERA Young Adult Follow-up team